Three American citizen children, including a four-year-old battling cancer, have reportedly been deported alongside their mothers, according to legal advocates and organizations supporting the families.

Immigration and Customs Enforcement (ICE) officials in New Orleans are said to have removed the two mothers and three children—ages two, four, and seven—from Louisiana to Honduras, according to a statement from the American Civil Liberties Union (ACLU).

One of the children, who is suffering from stage 4 cancer, was deported without receiving necessary medication, a family lawyer revealed. Additionally, one of the mothers is reportedly pregnant.

Both families had been residing in the United States for years, but the ACLU described their removal as taking place “under deeply troubling circumstances that raise serious due process concerns.”

In one case, a family that includes a two-year-old girl born in Louisiana was taken into custody during a routine check-in at a New Orleans immigration office on April 22, according to legal filings. A court hearing is scheduled for May 19 to determine whether the family was denied due process.

The second family was detained on April 24, two days later, after ICE reportedly failed to respond to inquiries from their lawyers and relatives, the ACLU added.